While catalysis by aspartic proteases involves the direct hydrolytic attack of water on a peptide bond, catalysis by the serine protease…
NEET-PG
Definition and epidemiology Dent’s disease (OMIM #300009) refers to a heterogeneous group of X-linked disorders that have previously been reported…
GASTROENTEROLOGY Crohn’s disease is a relapsing condition characterised by transmural inflammation in the gastrointestinal tract. The cytokine tumour necrosis factor…
Alpha-1 antitrypsin deficiency, also known as alpha 1-proteinase inhibitor deficiency or, more simply, Alpha-1, is a genetic condition that increases…
Preeclampsia is a pregnancy-specific disorder that affects 3–5% (1, 2) of pregnant women worldwide and is one of the most…
MUSCLES Muscles that provide action to the TMJ are the masseter, temporalis, and pterygoid along with a group which are…
The sirtuins are a family of proteins that act predominantly as nicotinamide adenine dinucleotide (NAD)-dependent deacetylases. In mammals seven sirtuin…
Introduction Degeneration and liquefaction of the vitreous gel with age ultimately leads to formation of a posterior vitreous detachment (PVD),…
INTRODUCTION Systemic lupus erythematosus (SLE) is a chronic inflammatory disease of unknown cause that can affect the skin, joints, kidneys,…
Erythropoietin(EPO), a member of the type I cytokine superfamily, was first identified as the hormone that stimulates erythroid progenitors within…
Acute renal failure (ARF), characterized by sudden loss of the ability of the kidneys to excrete wastes, concentrate urine, conserve…
What is Flap Surgery? Flap surgery is a type of plastic surgery that uses tissues from another part of the…
Fuchs endothelial dystrophy (FED) is characterized by an asymmetrical, bilateral, slowly progressive edema of the cornea in elderly patients. When…